Study Shows Potential for Parkinsons Disease Rehabilitation

Is rehabilitation of Parkinsons Disease a realistic hope for sufferers? This study abstract seems to indicate there’s value in further research and that’s good news, for us. We’re considering a proposal for more FP7 research, on precisely this topic. 🙂

Watch this space!

Does Cueing Training Improve Physical Activity in Patients With Parkinson’s Disease?

  1. Inge Lim, PhD

    1. VU University Medical Center, Amsterdam, the Netherlands
  1. Erwin van Wegen, PhD

    1. VU University Medical Center, Amsterdam, the Netherlands, e.vanwegen@vumc.nl
  1. Diana Jones, PhD

    1. Northumbria University, Newcastle upon Tyne, United Kingdom
  1. Lynn Rochester, PhD

    1. Northumbria University, Newcastle upon Tyne, United Kingdom, Newcastle University, Newcastle upon Tyne, United Kingdom
  1. Alice Nieuwboer, PhD

    1. Katholieke Universiteit, Leuven, Belgium
  1. Anne-Marie Willems, PhD

    1. Katholieke Universiteit, Leuven, Belgium
  1. Katherine Baker, PhD

    1. Northumbria University, Newcastle upon Tyne, United Kingdom
  1. Vicki Hetherington, MSc

    1. Northumbria University, Newcastle upon Tyne, United Kingdom
  1. Gert Kwakkel, PhD

    1. VU University Medical Center, Amsterdam, the Netherlands

Abstract

Background. Patients with Parkinson’s disease (PD) are encouraged to stay active to maintain their mobility. Ambulatory activity monitoring (AM) provides an objective way to determine type and amount of gait-related daily activities. Objective . To investigate the effects of a home cueing training program on functional walking activity in PD. Methods. In a single-blind, randomized crossover trial, PD patients allocated to early intervention received cueing training for 3 weeks, whereas the late intervention group received training in the following 3 weeks. Training was applied at home, using a prototype cueing device. AM was applied at baseline, 3, 6, and 12 weeks in the patient’s home, to record body movements. Postures and motions were classified as percentage of total time spent on (a) static activity, further specified as % sitting and % standing, and (b) % dynamic activity, further specified as % walking, % walking periods exceeding 5 seconds (W>” xbd=”1983″ xhg=”1960″ ybd=”1440″ yhg=”1401″/>5s) and 10 seconds (W>10s). Random coefficient analysis was applied. Results. A total of 153 patients participated in this trial. Significant improvements were found for dynamic activity (β= 4.46; P < .01), static activity (β=-3.34; P < .01), walking (β= 4.23; P < .01), W>5s (β = 2.63; P < .05), and W>10s (β = 2.90; P < .01). All intervention effects declined significantly at 6 weeks follow-up. Conclusion. Cueing training in PD patients’ own home significantly improves the amount of walking as recorded by AM. Treatment effects reduced after the intervention period, pointing to the need for permanent cueing devices and follow-up cueing training.

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